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The research was funded by the National Institute of General Medical Sciences of the National Institutes of Health.



美國倫斯勒理工學院(位於紐約州特洛伊市)、海洋生物嘗試室(位於麻薩諸塞州伍茲霍爾市)及路易斯安那州立大學衛生科學中心的研究人員們已發現,中間體內遺傳物資RNA的存在翻譯中間體是每細胞中,確保細胞恰當分裂的組織化構造物。

翻譯:許東榮

“Since RNA guides the translation of genes into proteins, knowing more about its role(s) in the centrosome may help researchers better understand the progression of diseases such as cancer翻譯社 which has been linked to abnormal centrosome numbers in tumor cells,” says Palazzo.
Palazzo
宣稱:「由於RNA引導構成卵白質的基因轉譯進程,是以知曉更多攸關RNA於中間體內的腳色,可能有助於研究人員們更深切瞭解,諸如癌症等疾病的進展進程,癌症已與腫瘤細胞中,異常的中間體數量被聯繫在一起。」

Palazzo’s laboratory isolated clam centrosomes and Mark Alliegro and Mary Anne Alliegro of LSU Health Sciences Center analyzed the centrosomes for RNA content.
倫斯勒工學院生物學傳授,兼生物手藝暨跨學科研究中間主任,Robert Palazzo宣稱:「他們的研究供應了,RNA存在於蛤蜊細胞中間體內的直接生化證據。」Palazzo的實行室星散了蛤蜊的中間體,為了得知RNA內含物,路易斯安那州立大學衛生科學中間的Mark AlliegroMary Anne Alliegro剖析了此些中間體。

“Although the possibility of DNA inside the centrosome of the cell has been ruled out by others’ previous work, the presence of RNA had not been confirmed or denied until now,” says Palazzo. “Our results show there are at least five specific forms of RNA in the clam cell centrosome which could be related to structure, encoding of proteins翻譯社 or the regulation of organism development. The specific role or function of the RNA in the centrosome and its possible involvement in the development of animals will be significant questions in continuing studies.”
Palazzo
傳播鼓吹:「固然,先前的其他研究已解除,DNA於細胞中心體內的可能性翻譯不外,迄今RNA的存在未曾被證實或否認翻譯他們的研究成效顯示,於蛤蜊細胞中心體內最少有5種,可能與卵白質的構造、暗碼編譯,或調理生物發育有所聯系關系的特殊型RNA翻譯在後續研究中,中間體內RNA的確切角色或功能,及其在動物發育中的可能聯系關系性,會是意義重大的問題翻譯

Researchers at Rensselaer Polytechnic Institute, the Marine Biological Laboratory (MBL) in Woods Hole, and Louisiana State University (LSU) Health Sciences Center have discovered the presence of the genetic material RNA in the centrosome, the organizing structure inside each cell that assures proper cell division.

The eggs develop fast翻譯社 entering the process of cell division less than 15 minutes after fertilization翻譯社 and翻譯社 once fertilized, divide in synch every 30-50 minutes — providing billions of biochemically identical cells to study.



是以,一旦受精,同步割裂每3050分鐘,能供給數十億供研究之生化上完全不異的細胞。

蛤蜊蛋成長快速,在受精後不及15分鐘,便進入細胞盤據的過程。


該項研究是由美國國家衛生研究院所屬國度綜合醫學科學研究所幫助。

 

Using a purification technique Palazzo developed at the MBL翻譯社 the scientists were able to isolate relatively large quantities of clam centrosomes for their research. Palazzo collaborated with Mark Alliegro and Mary Anne Alliegro during summers at the MBL.
利用Palazzo於海洋生物實驗室研發的純化手藝,些科學家能分離相對上大量的蛤蜊中間體,供進行研究。

 

The findings翻譯社 detailed June 5 in the online early edition of the journal Proceedings of the National Academy of Sciences, present evidence that individual centrosomes within a cell may carry their own genetic material.
此些胪陳於200665日網路版《美國國度科學院院刊》中的研究發現提出了,於細胞內各個中間體可能具有各自遺傳物資的證據。

The study on surf clam centrosomes was initiated at the MBL翻譯社 an international biological research center where scientists use locally abundant marine organisms like surf clams and their eggs as research models. Clam eggs are modeled as simple versions of human cells翻譯社 and biologists who study cell division value them for several reasons, according to Palazzo.
該項針對蛤蜊中間體的研究,是由美國私家、非營利組織的海洋生物實行室(一處國際生物研究中間)所建議,在此科學家們哄騙本地豐富的海洋生物,像北寄馬蛤蜊及其蛋作為研究樣本。憑據Palazzo的說法,由於諸多來由,蛤蜊蛋被充任為人類細胞的樣板模子,是以研究細胞盤據的生物學家們極正視它們。

“Our research provides direct biochemical evidence that RNA is present in the centrosomes of clam cells,” says Robert Palazzo, professor of biology and director of the Center for Biotechnology and Interdisciplinary Studies at Rensselaer.

http://news.rpi.edu/update.do?artcenterkey=1580&setappvar=page(1)



引用自: http://mypaper.pchome.com.tw/peregrine/post/1370830326有關翻譯的問題歡迎諮詢華頓翻譯社
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